This error message appears when the device thinks that its EStop input is active. There are a few things to check:
(1) Make sure the jumper on J14 is on the two pins closest to the corner of the board (and not on the pin closest to the "J14" silkscreen).
(2) Make sure there is nothing connected to J14 pin 1 (the terminal closest to the "J14" silkscreen and labeled "Fault").
(3) When installing the jumper, first make sure the screw terminals are fully open (turn the screwdriver counter-clockwise when looking down from above the board). This sounds trivial, but the screw terminals are "rising elevator" type, and only make reliable connections when the clamp is raised up onto the wire by turning the screwdriver clockwise when looking down from above the board.
(4) Look at the two right-angle LEDs on the PMDX-424, specifically the red (top) one. If the EStop input is active (i.e. the EStop terminal not tied to its GND, or the Fault input IS tied to its GND) the red LED will remain lit always. If the EStop is NOT active, the red LED will turn off when the plug-in establishes communication with the device.
(5) In Mach4, go to the "Diagnostics" menu and select our device. Then click on the "Real time display" button (you can then close the diagnostics dialog and leave the real-time display running. Look at the EStop indicator on the real-time display. If it is a bright red, then the device thinks its EStop input is active.
(6) Do you have anything connected to the "Fault" terminal on J14?
(7) Do you have anything connected to either of the two 26-pin ribbon headers on the PMDX-424?
(8) Try removing all connections to the PMDX-424 except for power and the EStop jumper (you can simply un-plug the screw terminal connectors). Do you still have this problem?
Bob